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@ARTICLE{Claeser:863051,
      author       = {Claeser, Robert and Zimmermann, Markus and Shah, N. J.},
      title        = {{S}ub‐millimeter {T} 1 mapping of rapidly relaxing
                      compartments with gradient delay corrected spiral {TAPIR}
                      and compressed sensing at 3{T}},
      journal      = {Magnetic resonance in medicine},
      volume       = {82},
      number       = {4},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {FZJ-2019-03173},
      pages        = {1288-1300},
      year         = {2019},
      abstract     = {PurposeThe TAPIR sequence is an accurate and efficient
                      method for T1 mapping. It combines a slice‐interleaving
                      Look‐Locker read‐out with an acquisition of multiple
                      k‐space lines in 1 shot. Whereas the acquisition of
                      multiple lines per excitation increases imaging speed, the
                      corresponding increase in TR and TE is detrimental to the T1
                      fitting performance. This is especially problematic for
                      substances exhibiting rapid T2* relaxation (e.g., myelin
                      water).MethodsThe T1 fitting performance of TAPIR is
                      enhanced by using an interleaved spiral read‐out with
                      shorter TE and TR. Furthermore, an improvement to a method
                      for fast gradient delay estimation is presented. Whereas
                      previous methods assume the gradient delay to be stationary,
                      the presented approach corrects the spiral k‐space
                      trajectory by using a polynomial fit of the measured
                      gradient delays.ResultsGradient delay artifacts are largely
                      eliminated, requiring very little additional scanning time.
                      The sampling efficiency of the spiral read‐out allows for
                      a significant reduction of the acquisition time in
                      comparison to Cartesian TAPIR. Spiral TAPIR enables the
                      sampling of more slices and an accurate measurement of
                      rapidly relaxing compartments. Over a wide T1 range
                      (448–3115 ms), spiral TAPIR reduces the mean fitting error
                      from $−2.5\%$ to $−0.1\%.$ Combining $50\%$
                      undersampling with the shorter TR of spiral TAPIR, an
                      increase in imaging speed by a factor of up to 3.3 was
                      achieved.ConclusionUsing a spiral read‐out trajectory, the
                      established TAPIR sequence enables measurement of rapidly
                      relaxing T1 compartments, while improving T1 mapping
                      performance and imaging speed.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31148282},
      UT           = {WOS:000483917000005},
      doi          = {10.1002/mrm.27797},
      url          = {https://juser.fz-juelich.de/record/863051},
}