%0 Journal Article
%A Zlatopolskiy, Boris D.
%A Zischler, Johannes
%A Krapf, Philipp
%A Richarz, Raphael
%A Lauchner, Katharina
%A Neumaier, Bernd
%T Minimalist approach meets green chemistry: Synthesis of 18F-labeled (hetero)aromatics in pure ethanol
%J Journal of labelled compounds and radiopharmaceuticals
%V 62
%N 8
%@ 0362-4803
%C New York, NY [u.a.]
%I Wiley
%M FZJ-2019-03789
%P 404 - 410
%D 2019
%X The application of toxic solvents and additives is inevitable for most of the described protocols for 18F‐labeling. Herein, a novel “green” procedure for nucleophilic aromatic radiofluorination of highly activated (hetero)aromatic substrates in pure EtOH is described. Using this method a series of 18F‐labeled (hetero)arenes have been synthesized in radiochemical yields (RCYs) of up to 97%.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:31162691
%U <Go to ISI:>//WOS:000475397300006
%R 10.1002/jlcr.3776
%U https://juser.fz-juelich.de/record/863802