TY  - JOUR
AU  - Zlatopolskiy, Boris D.
AU  - Zischler, Johannes
AU  - Krapf, Philipp
AU  - Richarz, Raphael
AU  - Lauchner, Katharina
AU  - Neumaier, Bernd
TI  - Minimalist approach meets green chemistry: Synthesis of 18F-labeled (hetero)aromatics in pure ethanol
JO  - Journal of labelled compounds and radiopharmaceuticals
VL  - 62
IS  - 8
SN  - 0362-4803
CY  - New York, NY [u.a.]
PB  - Wiley
M1  - FZJ-2019-03789
SP  - 404 - 410
PY  - 2019
AB  - The application of toxic solvents and additives is inevitable for most of the described protocols for 18F‐labeling. Herein, a novel “green” procedure for nucleophilic aromatic radiofluorination of highly activated (hetero)aromatic substrates in pure EtOH is described. Using this method a series of 18F‐labeled (hetero)arenes have been synthesized in radiochemical yields (RCYs) of up to 97%.
LB  - PUB:(DE-HGF)16
C6  - pmid:31162691
UR  - <Go to ISI:>//WOS:000475397300006
DO  - DOI:10.1002/jlcr.3776
UR  - https://juser.fz-juelich.de/record/863802
ER  -