% IMPORTANT: The following is UTF-8 encoded. This means that in the presence % of non-ASCII characters, it will not work with BibTeX 0.99 or older. % Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or % “biber”. @ARTICLE{Mechsner:864465, author = {Mechsner, Bastian and Böse, Dietrich and Hogenkamp, Fabian and Ledermann, Nadia and Hartmann, Rudolf and Bochinsky, Kevin and Frey, Wolfgang and Pietruszka, Jörg}, title = {{E}nantioselective total synthesis of altersolanol {A} and {N}}, journal = {Bioorganic $\&$ medicinal chemistry}, volume = {27}, number = {13}, issn = {0968-0896}, address = {Amsterdam [u.a.]}, publisher = {Elsevier}, reportid = {FZJ-2019-04246}, pages = {2991 - 2997}, year = {2019}, abstract = {The development of the first enantioselective total synthesis of altersolanol N is reported. The decisive step of the synthesis is the enantioselective formation of the tetrahydroanthraquinone nucleus by a [4 + 2]-cycloaddition in high yield and with excellent diastereo- and enantioselectivity (>95:5 dr and 95:5 er). In addition, a demanding selective monoacetylation of the OH group at the C-2 position was achieved: an epoxide ring opening with the participation of a neighbouring acetyl group could be established. The route proved to be an efficient alternative to also access enantiomerically pure altersolanol A.}, cin = {IBOC / IBG-1 / ICS-6}, ddc = {610}, cid = {I:(DE-Juel1)IBOC-20090406 / I:(DE-Juel1)IBG-1-20101118 / I:(DE-Juel1)ICS-6-20110106}, pnm = {581 - Biotechnology (POF3-581)}, pid = {G:(DE-HGF)POF3-581}, typ = {PUB:(DE-HGF)16}, pubmed = {pmid:31072649}, UT = {WOS:000470106900027}, doi = {10.1016/j.bmc.2019.04.033}, url = {https://juser.fz-juelich.de/record/864465}, }