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Contribution to a book | FZJ-2019-04349 |
; ; ; ;
2019
Springer New York
New York, NY
ISBN: 978-1-4939-8872-3 (print), 978-1-4939-8873-0 (electronic)
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Please use a persistent id in citations: doi:10.1007/978-1-4939-8873-0_2
Abstract: Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of proteins involved in autophagy by using X-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy. Further we will provide instructions how to perform a molecular dynamics (MD) simulation using GABARAP as example protein.
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