Contribution to a book FZJ-2019-04349

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Structural Studies of Autophagy-Related Proteins

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2019
Springer New York New York, NY
ISBN: 978-1-4939-8872-3 (print), 978-1-4939-8873-0 (electronic)

Autophagy / Ktistakis, Nicholas (Editor) Chapter 2 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-8872-3=978-1-4939-8873-0 ; doi:10.1007/978-1-4939-8873-0 New York, NY : Springer New York, Methods in Molecular Biology 1880, 17 - 56 () [10.1007/978-1-4939-8873-0_2]

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Abstract: Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of proteins involved in autophagy by using X-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy. Further we will provide instructions how to perform a molecular dynamics (MD) simulation using GABARAP as example protein.

Classification:

Contributing Institute(s):
  1. Strukturbiochemie (ICS-6)
Research Program(s):
  1. 552 - Engineering Cell Function (POF3-552) (POF3-552)

Appears in the scientific report 2019
Database coverage:
Medline ; NCBI Molecular Biology Database ; SCOPUS
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 Record created 2019-08-22, last modified 2021-04-26


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