TY - CHAP AU - Schwarten, Melanie AU - Weiergräber, Oliver H. AU - Petrović, Dušan AU - Strodel, Birgit AU - Willbold, Dieter TI - Structural Studies of Autophagy-Related Proteins VL - 1880 CY - New York, NY PB - Springer New York M1 - FZJ-2019-04349 SN - 978-1-4939-8872-3 (print) T2 - Methods in Molecular Biology SP - 17 - 56 PY - 2019 AB - Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of proteins involved in autophagy by using X-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy. Further we will provide instructions how to perform a molecular dynamics (MD) simulation using GABARAP as example protein. LB - PUB:(DE-HGF)7 C6 - pmid:30610688 UR - <Go to ISI:>//WOS:000623746900003 DO - DOI:10.1007/978-1-4939-8873-0_2 UR - https://juser.fz-juelich.de/record/864647 ER -