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@ARTICLE{Svetlova:865134,
      author       = {Svetlova, Anastasia and Ellieroth, Jana and Milos, Frano
                      and Maybeck, Vanessa and Offenhäusser, Andreas},
      title        = {{C}omposite {L}ipid {B}ilayers from {C}ell {M}embrane
                      {E}xtracts and {A}rtificial {M}ixes as a {C}ell {C}ulture
                      {P}latform},
      journal      = {Langmuir},
      volume       = {35},
      number       = {24},
      issn         = {1520-5827},
      address      = {Washington, DC},
      publisher    = {ACS Publ.},
      reportid     = {FZJ-2019-04686},
      pages        = {8076 - 8084},
      year         = {2019},
      abstract     = {An artificial lipid bilayer is the closest possible model
                      for the cell membrane. Despite that, current methods of
                      lipid bilayer assembly and functionalization do not provide
                      a satisfactory mimic of the cell–cell contact due to the
                      inability to recreate an asymmetrical multicomponent system.
                      In the current work, a method to produce an integrated
                      solid-supported lipid bilayer combining natural extracts
                      from cell membranes and artificially made lipid vesicles is
                      proposed. This simple method allows delivery of
                      transmembrane proteins and components of the extracellular
                      matrix into the substrate. Biocompatibility of the composite
                      natural/artificial lipid bilayers is evaluated by their
                      interactions with the cardiomyocyte-like HL-1 cell line.
                      Compared with fully artificial mixes, composite lipid
                      bilayers allow cells to adhere and develop a morphologically
                      more normal cytoskeleton.},
      cin          = {ICS-8},
      ddc          = {540},
      cid          = {I:(DE-Juel1)ICS-8-20110106},
      pnm          = {552 - Engineering Cell Function (POF3-552)},
      pid          = {G:(DE-HGF)POF3-552},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31055920},
      UT           = {WOS:000472682600054},
      doi          = {10.1021/acs.langmuir.9b00763},
      url          = {https://juser.fz-juelich.de/record/865134},
}