Journal Article FZJ-2019-04730

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Comment on “Hypometabolic gliomas on FET-PET - Is there an inverted U-curve for survival?”, Kamson 2019, Neuro-Oncology

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2019
Oxford Univ. Press Oxford

Neuro-Oncology 21(12), 1612-1613 () [10.1093/neuonc/noz173]

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Abstract: With great interest we read the editorial by Kamson entitled “Hypometabolic Gliomas on FET-PET—Is There an Inverted U-Curve for Survival?” in Neuro-Oncology1 referring to our publication regarding the clinical relevance of photopenic defects on O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET in glioma patients.2 In that paper, we identified within 100 patients with FET-PET–negative gliomas a subgroup of patients who even exhibit photopenic defects and had, moreover, an unfavorable outcome compared with gliomas with indifferent FET uptake (isometabolic gliomas). From our point of view, the frequency of photopenic defects is even lower than 10% (ie, ~5%). In his editorial, the author raised valuable new thoughts and ideas that are worth discussing.

Classification:

Contributing Institute(s):
  1. Kognitive Neurowissenschaften (INM-3)
  2. Physik der Medizinischen Bildgebung (INM-4)
Research Program(s):
  1. 572 - (Dys-)function and Plasticity (POF3-572) (POF3-572)

Appears in the scientific report 2019
Database coverage:
Medline ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; NationallizenzNationallizenz ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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