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@ARTICLE{Contente:867642,
      author       = {Contente, Martina Letizia and Dall’Oglio, Federica and
                      Annunziata, Francesca and Molinari, Francesco and
                      Rabuffetti, Marco and Romano, Diego and Tamborini, Lucia and
                      Rother, Dörte and Pinto, Andrea},
      title        = {{S}tereoselective {R}eduction of {P}rochiral {C}yclic
                      1,3-{D}iketones {U}sing {D}ifferent {B}iocatalysts},
      journal      = {Catalysis letters},
      volume       = {150},
      issn         = {1572-879X},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V},
      reportid     = {FZJ-2019-06263},
      pages        = {1176-1185},
      year         = {2020},
      abstract     = {We have developed biocatalytic methods for the
                      stereoselective reduction of cyclic prochiral 1,3-diketones
                      for the production of optically active β-hydroxyketones
                      and/or 1,3-diols. The recombinant ketoreductase KRED1-Pglu
                      (formulated as purified catalyst) and whole cells of wild
                      type Escherichia coli DE3 Star were used as biocatalysts,
                      displaying different and sometimes complementary
                      stereoselectivity, thus allowing the preparation of
                      stereochemically pure β-hydroxyketones $(12–66\%$
                      isolated $yields, > 99\%$ e.e.) and 1,3-diols
                      $(40–60\%$ isolated $yields, > 99\%$ e.e.).},
      cin          = {IBG-1},
      ddc          = {660},
      cid          = {I:(DE-Juel1)IBG-1-20101118},
      pnm          = {581 - Biotechnology (POF3-581)},
      pid          = {G:(DE-HGF)POF3-581},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000495029200001},
      doi          = {10.1007/s10562-019-03015-y},
      url          = {https://juser.fz-juelich.de/record/867642},
}