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@ARTICLE{Tahmasian:874657,
author = {Tahmasian, Masoud and Samea, Fateme and Khazaie, Habibolah
and Zarei, Mojtaba and Kharabian Masouleh, Shahrzad and
Hoffstaedter, Felix and Camilleri, Julia and Kochunov, Peter
and Yeo, B. T. Thomas and Eickhoff, Simon Bodo and Valk,
Sofie Louise},
title = {{T}he interrelation of sleep and mental and physical health
is anchored in grey-matter neuroanatomy and under genetic
control},
journal = {Communications biology},
volume = {3},
number = {1},
issn = {2399-3642},
address = {London},
publisher = {Springer Nature},
reportid = {FZJ-2020-01573},
pages = {171},
year = {2020},
abstract = {Humans need about seven to nine hours of sleep per night.
Sleep habits are heritable, associated with brain function
and structure, and intrinsically related to well-being,
mental, and physical health. However, the biological basis
of the interplay of sleep and health is incompletely
understood. Here we show, by combining neuroimaging and
behavioral genetic approaches in two independent large-scale
datasets (HCP (n = 1106), age range: 22–37, eNKI
(n = 783), age range: 12–85), that sleep, mental, and
physical health have a shared neurobiological basis in grey
matter anatomy; and that these relationships are driven by
shared genetic factors. Though local associations between
sleep and cortical thickness were inconsistent across
samples, we identified two robust latent components,
highlighting the multivariate interdigitation of sleep,
intelligence, BMI, depression, and macroscale cortical
structure. Our observations provide a system-level
perspective on the interrelation of sleep, mental, and
physical conditions, anchored in grey-matter neuroanatomy.},
cin = {INM-7},
ddc = {570},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32273564},
UT = {WOS:000525723200001},
doi = {10.1038/s42003-020-0892-6},
url = {https://juser.fz-juelich.de/record/874657},
}