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@ARTICLE{Bscher:877669,
      author       = {Büscher, Tobias and Gompper, Gerhard and Elgeti, Jens and
                      Diez, Angel L.},
      title        = {{I}nstability and fingering of interfaces in growing
                      tissue},
      journal      = {New journal of physics},
      volume       = {22},
      issn         = {1367-2630},
      address      = {[London]},
      publisher    = {IOP73379},
      reportid     = {FZJ-2020-02379},
      pages        = {083005},
      year         = {2020},
      abstract     = {Interfaces in tissues are ubiquitous, both between tissue
                      and environment as well as between populations of different
                      cell types. The propagation of an interface can be driven
                      mechanically. Computer simulations of growing tissues are
                      employed to study the stability of the interface between two
                      tissues on a substrate. From a mechanical perspective, the
                      dynamics and stability of this system is controlled mainly
                      by four parameters of the respective tissues: (i) the
                      homeostatic stress (ii) cell motility (iii) tissue viscosity
                      and (iv) substrate friction. For propagation driven by a
                      difference in homeostatic stress, the interface is stable
                      for tissue-specific substrate friction even for very large
                      differences of homeostatic stress; however, it becomes
                      unstable above a critical stress difference when the tissue
                      with the larger homeostatic stress has a higher viscosity. A
                      small difference in directed bulk motility between the two
                      tissues suffices to result in propagation with a stable
                      interface, even for otherwise identical tissues. Larger
                      differences in motility force, however, result in a
                      finite-wavelength instability of the interface.
                      Interestingly, the instability is apparently bound by
                      nonlinear effects and the amplitude of the interface
                      undulations only grows to a finite value in time.},
      cin          = {IBI-5},
      ddc          = {530},
      cid          = {I:(DE-Juel1)IBI-5-20200312},
      pnm          = {553 - Physical Basis of Diseases (POF3-553)},
      pid          = {G:(DE-HGF)POF3-553},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000560125300001},
      doi          = {10.1088/1367-2630/ab9e88},
      url          = {https://juser.fz-juelich.de/record/877669},
}