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@ARTICLE{Choi:878002,
author = {Choi, Seung-Min and Jeong, Jae-Chan and Kim, Jinsun and
Lim, Eul-Gyoon and Kim, Chang-beom and Park, Sang-Jin and
Song, Dae-Yong and Krause, Hans-Joachim and Hong, Hyobong
and Kweon, In So},
title = {{A} novel three-dimensional magnetic particle imaging
system based on the frequency mixing for the point-of-care
diagnostics},
journal = {Scientific reports},
volume = {10},
number = {1},
issn = {2045-2322},
address = {[London]},
publisher = {Macmillan Publishers Limited, part of Springer Nature},
reportid = {FZJ-2020-02576},
pages = {11833},
year = {2020},
abstract = {The magnetic particle imaging (MPI) is a technology that
can image the concentrations of the superparamagnetic iron
oxide nanoparticles (SPIONs) which can be used in biomedical
diagnostics and therapeutics as non-radioactive tracers. We
proposed a point-of-care testing MPI system (PoCT- MPI) that
can be used for preclinical use for imaging small rodents
(mice) injected with SPIONs not only in laboratories, but
also at emergency sites far from laboratories. In
particular, we applied a frequency mixing magnetic detection
method to the PoCT-MPI, and proposed a hybrid field free
line generator to reduce the power consumption, size and
weight of the system. The PoCT-MPI is 20 × 33 × 45 cm³ in
size and weighs less than 100 kg. It can image a
three-dimensional distribution of SPIONs injected into a
biosample with less than 120 Wh of power consumption. Its
detection limit is 0.13μL , 10 mg/mL, 1.3μg (Fe).},
cin = {IBI-3},
ddc = {600},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {523 - Controlling Configuration-Based Phenomena (POF3-523)},
pid = {G:(DE-HGF)POF3-523},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32678265},
UT = {WOS:000550057200146},
doi = {10.1038/s41598-020-68864-9},
url = {https://juser.fz-juelich.de/record/878002},
}