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@ARTICLE{Wolf:888252,
      author       = {Wolf, Nikolaus and Yuan, Xiaobo and Hassani, Hossein and
                      Milos, Frano and Mayer, Dirk and Breuer, Uwe and
                      Offenhäusser, Andreas and Wördenweber, Roger},
      title        = {{S}urface {F}unctionalization of {P}latinum {E}lectrodes
                      with {APTES} for {B}ioelectronic {A}pplications},
      journal      = {ACS applied bio materials},
      volume       = {3},
      number       = {10},
      issn         = {2576-6422},
      address      = {Washington, DC},
      publisher    = {ACS Publications},
      reportid     = {FZJ-2020-04799},
      pages        = {7113 - 7121},
      year         = {2020},
      abstract     = {The interface between electronic components and biological
                      objects plays a crucial role for the success of
                      bioelectronic devices. Since the electronics typically
                      include different elements such as an insulating substrate
                      in combination with conducting electrodes, an important
                      issue of bioelectronics involves tailoring and optimizing
                      the interface for any envisioned applications. In this
                      paper, we present a method for functionalizing insulating
                      substrates (SiO2) and metallic electrodes (Pt)
                      simultaneously with a stable monolayer of organic molecules
                      ((3-aminopropyl)triethoxysilane (APTES)). This monolayer is
                      characterized by a high molecule density, long term
                      stability, and a positive surface net charge and most likely
                      represents a self-assembled monolayer (SAM). It facilitates
                      a conversion of bio-unfriendly Pt surfaces into
                      biocompatible surfaces which allows cell growth (neurons) on
                      both functionalized components, SiO2 and Pt, which is
                      comparable to that of reference samples coated with
                      poly-L-lysine (PLL). Moreover, the functionalization greatly
                      improves the electronic cell-chip coupling thereby enabling
                      the recording of action potential signals of several mV at
                      APTES-functionalized Pt electrodes.},
      cin          = {IBI-3},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5244 - Information Processing in Neuronal Networks
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5244},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {35019371},
      UT           = {WOS:000619799800053},
      doi          = {10.1021/acsabm.0c00936},
      url          = {https://juser.fz-juelich.de/record/888252},
}