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@ARTICLE{Thieme:888306,
author = {Thieme, A. and Röske, S. and Faber, J. and Sulzer, P. and
Minnerop, Martina and Elben, S. and Jacobi, H. and Reetz, K.
and Dogan, I. and Barkhoff, M. and Konczak, J. and
Wondzinski, E. and Siebler, M. and Hetze, S. and Müller, O.
and Sure, U. and Schmahmann, J. D. and Klockgether, T. and
Synofzik, M. and Timmann, D.},
title = {{R}eference values for the {C}erebellar {C}ognitive
{A}ffective / {S}chahmann {S}yndrome {S}cale: {A}ge and
education matter},
journal = {Brain},
volume = {144},
number = {2},
issn = {0006-8950},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2020-04826},
pages = {e20},
year = {2021},
abstract = {During recent decades, many studies have yielded evidence
for cerebellar involvement in cognitive, emotional and
affective processes besides the well-known cerebellar
contribution to motor performance and learning (Koziol et
al., 2014; Marien et al., 2014; Van Overwalle et al., 2014;
Strata, 2015; Adamaszek et al., 2017; Kansal et al., 2017;
Guell et al., 2018; King et al., 2019). Cerebellar diseases
can result in executive, linguistic and visuospatial
dysfunctions as well as problems with the regulation of
emotion and affect. This combination of non-motor symptoms
has been named cerebellar cognitive affective/Schmahmann
syndrome (CCAS) (Schmahmann and Sherman, 1998). For many
years, diagnosis has relied on non-standardized bedside
cognitive examination and, if available, detailed
neuropsychological test batteries. A short and easily
applicable bedside test (CCAS Scale), published by Hoche et
al. (2018) in Brain, was developed to screen for CCAS and is
already in widespread use. We therefore believe that it is
important to share our recent findings that the reference
values published by Hoche and colleagues may apply only
within a limited age and education range, while their more
universal application may lead to a substantial number of
false-positive test results.},
cin = {INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {33367632},
UT = {WOS:000649446500007},
doi = {10.1093/brain/awaa417},
url = {https://juser.fz-juelich.de/record/888306},
}