Journal Article

FZJ-2020-04826

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Reference values for the Cerebellar Cognitive Affective / Schahmann Syndrome Scale: Age and education matter

Thieme, A. (Corresponding author) ; Röske, S. ; Faber, J. ; Sulzer, P. ; Minnerop, M.FZJ* ; Elben, S. ; Jacobi, H. ; Reetz, K. ; Dogan, I. ; Barkhoff, M. ; Konczak, J. ; Wondzinski, E. ; Siebler, M. ; Hetze, S. ; Müller, O. ; Sure, U. ; Schmahmann, J. D. ; Klockgether, T. ; Synofzik, M. ; Timmann, D.

2021
Oxford Univ. Press Oxford

This record in other databases:    

Please use a persistent id in citations: http://hdl.handle.net/2128/27399  doi:10.1093/brain/awaa417

Abstract: During recent decades, many studies have yielded evidence for cerebellar involvement in cognitive, emotional and affective processes besides the well-known cerebellar contribution to motor performance and learning (Koziol et al., 2014; Marien et al., 2014; Van Overwalle et al., 2014; Strata, 2015; Adamaszek et al., 2017; Kansal et al., 2017; Guell et al., 2018; King et al., 2019). Cerebellar diseases can result in executive, linguistic and visuospatial dysfunctions as well as problems with the regulation of emotion and affect. This combination of non-motor symptoms has been named cerebellar cognitive affective/Schmahmann syndrome (CCAS) (Schmahmann and Sherman, 1998). For many years, diagnosis has relied on non-standardized bedside cognitive examination and, if available, detailed neuropsychological test batteries. A short and easily applicable bedside test (CCAS Scale), published by Hoche et al. (2018) in Brain, was developed to screen for CCAS and is already in widespread use. We therefore believe that it is important to share our recent findings that the reference values published by Hoche and colleagues may apply only within a limited age and education range, while their more universal application may lead to a substantial number of false-positive test results.

---

Contributing Institute(s):

1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)

Research Program(s):

1. 5251 - Multilevel Brain Organization and Variability (POF4-525) (POF4-525)

Appears in the scientific report 2021

---

Database coverage:
; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 10 ; JCR ; Nationallizenz ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---