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000888841 1001_ $$00000-0002-9606-0408$$aMcCullough, J. W. S.$$b0$$eCorresponding author
000888841 245__ $$aTowards blood flow in the virtual human: efficient self-coupling of HemeLB
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000888841 520__ $$aMany scientific and medical researchers areworking towards the creation of avirtual human—a personalized digital copy of an individual—that will assistin a patient’s diagnosis, treatment and recovery. The complex nature of livingsystems means that the development of this remains a major challenge. Wedescribe progress in enabling the HemeLB lattice Boltzmann code to simulate3D macroscopic blood flowon a full human scale. Significant developments inmemory management and load balancing allow near linear scaling performanceof the code on hundreds of thousands of computer cores. Integral tothe construction of a virtual human, we also outline the implementation of aself-coupling strategy for HemeLB. This allows simultaneous simulation ofarterial and venous vascular trees based on human-specific geometries.
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000888841 7001_ $$00000-0002-9984-2720$$aRichardson, R. A.$$b1
000888841 7001_ $$0P:(DE-Juel1)179111$$aPatronis, A.$$b2$$ufzj
000888841 7001_ $$0P:(DE-Juel1)132124$$aHalver, R.$$b3$$ufzj
000888841 7001_ $$0P:(DE-HGF)0$$aMarshall, R.$$b4
000888841 7001_ $$0P:(DE-HGF)0$$aRuefenacht, M.$$b5
000888841 7001_ $$0P:(DE-Juel1)132302$$aWylie, B. J. N.$$b6$$ufzj
000888841 7001_ $$0P:(DE-HGF)0$$aOdaker, T.$$b7
000888841 7001_ $$0P:(DE-Juel1)131906$$aWiedemann, M.$$b8
000888841 7001_ $$0P:(DE-HGF)0$$aLloyd, B.$$b9
000888841 7001_ $$0P:(DE-HGF)0$$aNeufeld, E.$$b10
000888841 7001_ $$0P:(DE-Juel1)132274$$aSutmann, Godehard$$b11
000888841 7001_ $$0P:(DE-HGF)0$$aSkjellum, A.$$b12
000888841 7001_ $$0P:(DE-HGF)0$$aKranzlmüller, D.$$b13
000888841 7001_ $$00000-0002-8787-7256$$aCoveney, P. V.$$b14$$eCorresponding author
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