Journal Article

FZJ-2020-05255

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Towards blood flow in the virtual human: efficient self-coupling of HemeLB

McCullough, J. W. S. (Corresponding author) ; Richardson, R. A. ; Patronis, A.FZJ* ; Halver, R.FZJ* ; Marshall, R. ; Ruefenacht, M. ; Wylie, B. J. N.FZJ* ; Odaker, T. ; Wiedemann, M. ; Lloyd, B. ; Neufeld, E. ; Sutmann, G.FZJ* ; Skjellum, A. ; Kranzlmüller, D. ; Coveney, P. V. (Corresponding author)

2021
Royal Society Publishing London

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Please use a persistent id in citations: http://hdl.handle.net/2128/26553  doi:10.1098/rsfs.2019.0119

Abstract: Many scientific and medical researchers areworking towards the creation of avirtual human—a personalized digital copy of an individual—that will assistin a patient’s diagnosis, treatment and recovery. The complex nature of livingsystems means that the development of this remains a major challenge. Wedescribe progress in enabling the HemeLB lattice Boltzmann code to simulate3D macroscopic blood flowon a full human scale. Significant developments inmemory management and load balancing allow near linear scaling performanceof the code on hundreds of thousands of computer cores. Integral tothe construction of a virtual human, we also outline the implementation of aself-coupling strategy for HemeLB. This allows simultaneous simulation ofarterial and venous vascular trees based on human-specific geometries.

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Contributing Institute(s):

1. Jülich Supercomputing Center (JSC)

Research Program(s):

1. 5111 - Domain-Specific Simulation & Data Life Cycle Labs (SDLs) and Research Groups (POF4-511) (POF4-511)
2. 5112 - Cross-Domain Algorithms, Tools, Methods Labs (ATMLs) and Research Groups (POF4-511) (POF4-511)
3. E-CAM - An e-infrastructure for software, training and consultancy in simulation and modelling (676531) (676531)
4. POP - Performance Optimisation and Productivity (676553) (676553)
5. POP2 - Performance Optimisation and Productivity 2 (824080) (824080)
6. CompBioMed - A Centre of Excellence in Computational Biomedicine (675451) (675451)
7. CompBioMed2 - A Centre of Excellence in Computational Biomedicine (823712) (823712)
8. ATMLPP - ATML Parallel Performance (ATMLPP) (ATMLPP)

Appears in the scientific report 2021

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Database coverage:
; ; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Essential Science Indicators ; IF < 5 ; JCR ; National-Konsortium ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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