TY  - JOUR
AU  - McCullough, J. W. S.
AU  - Richardson, R. A.
AU  - Patronis, A.
AU  - Halver, R.
AU  - Marshall, R.
AU  - Ruefenacht, M.
AU  - Wylie, B. J. N.
AU  - Odaker, T.
AU  - Wiedemann, M.
AU  - Lloyd, B.
AU  - Neufeld, E.
AU  - Sutmann, Godehard
AU  - Skjellum, A.
AU  - Kranzlmüller, D.
AU  - Coveney, P. V.
TI  - Towards blood flow in the virtual human: efficient self-coupling of HemeLB
JO  - Interface focus
VL  - 11
IS  - 1
SN  - 2042-8901
CY  - London
PB  - Royal Society Publishing
M1  - FZJ-2020-05255
SP  - 20190119 -
PY  - 2021
AB  - Many scientific and medical researchers areworking towards the creation of avirtual human—a personalized digital copy of an individual—that will assistin a patient’s diagnosis, treatment and recovery. The complex nature of livingsystems means that the development of this remains a major challenge. Wedescribe progress in enabling the HemeLB lattice Boltzmann code to simulate3D macroscopic blood flowon a full human scale. Significant developments inmemory management and load balancing allow near linear scaling performanceof the code on hundreds of thousands of computer cores. Integral tothe construction of a virtual human, we also outline the implementation of aself-coupling strategy for HemeLB. This allows simultaneous simulation ofarterial and venous vascular trees based on human-specific geometries.
LB  - PUB:(DE-HGF)16
C6  - 33335704
UR  - <Go to ISI:>//WOS:000600128700002
DO  - DOI:10.1098/rsfs.2019.0119
UR  - https://juser.fz-juelich.de/record/888841
ER  -