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100 1 _ |0 0000-0002-9606-0408
|a McCullough, J. W. S.
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245 _ _ |a Towards blood flow in the virtual human: efficient self-coupling of HemeLB
260 _ _ |a London
|b Royal Society Publishing
|c 2021
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520 _ _ |a Many scientific and medical researchers areworking towards the creation of avirtual human—a personalized digital copy of an individual—that will assistin a patient’s diagnosis, treatment and recovery. The complex nature of livingsystems means that the development of this remains a major challenge. Wedescribe progress in enabling the HemeLB lattice Boltzmann code to simulate3D macroscopic blood flowon a full human scale. Significant developments inmemory management and load balancing allow near linear scaling performanceof the code on hundreds of thousands of computer cores. Integral tothe construction of a virtual human, we also outline the implementation of aself-coupling strategy for HemeLB. This allows simultaneous simulation ofarterial and venous vascular trees based on human-specific geometries.
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