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@INPROCEEDINGS{Koh:891637,
author = {Koh, Seong-Ryong and Kim, J. and Lintermann, Andreas},
title = {{N}umerical {A}nalysis of {O}scillatory {F}lows in the
{H}uman {B}rain by a {L}attice-{B}oltzmann {M}ethod},
reportid = {FZJ-2021-01633},
pages = {1-12},
year = {2021},
comment = {14th WCCM-ECCOMAS Congress : [Proceedings] - CIMNE, 2021. -
ISBN - doi:10.23967/wccm-eccomas.2020.226},
booktitle = {14th WCCM-ECCOMAS Congress :
[Proceedings] - CIMNE, 2021. - ISBN -
doi:10.23967/wccm-eccomas.2020.226},
abstract = {The cerebrospinal fluid flow in a brain ventricular system
is analyzed by the numerical approach employing a
lattice-Boltzmann (LB) method. The cerebrospinal fluid,
which surrounds the human brain and spinal cord, fills the
cerebral ventricles as well as the cranial and subarachnoid
spaces. Diseases in a central nerve system disrupt the flow
circulation which influences on a number of vital functions.
A computational fluid dynamics technique is used to
determine the member geometry impact on the flow motion. The
numerical analysis focuses on building a simulation-based
basis for testing/optimizing therapeutical methods and
understanding the pathophysiology. Magnetic resonance (MR)
imaging is exploited to obtain realistic geometries in a
brain ventricular system. The computational domain is
discretized by a hierarchical Cartesian octree mesh. The
numerical procedure based on an LB method overcomes the
difficulties raised by typical finite-difference and
finite-volume methods on high-performance computing (HPC)
systems. An oscillating flow boundary condition is defined
to resolve the kinetic behavior of cerebrospinal fluid in a
cardiac cycle. The three-dimensional structures captured in
the cerebral ventricles show a qualitative agreement with an
observation based on an MR velocity mapping. The simulation
on a HPC system is able to provide further insights into the
transport from brain to spinal cord.},
month = {Jan},
date = {2021-01-11},
organization = {14th WCCM-ECCOMAS Congress, digital
(digital), 11 Jan 2021 - 15 Jan 2021},
cin = {JSC},
ddc = {610},
cid = {I:(DE-Juel1)JSC-20090406},
pnm = {5111 - Domain-Specific Simulation $\&$ Data Life Cycle Labs
(SDLs) and Research Groups (POF4-511)},
pid = {G:(DE-HGF)POF4-5111},
typ = {PUB:(DE-HGF)8 / PUB:(DE-HGF)7},
doi = {10.23967/wccm-eccomas.2020.226},
url = {https://juser.fz-juelich.de/record/891637},
}