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@ARTICLE{Yao:892048,
      author       = {Yao, Li and Yang, Chengmin and Zhang, Wenjing and Li, Siyi
                      and Li, Qian and Chen, Lizhou and Lui, Su and Kemp, Graham
                      J. and Biswal, Bharat B. and Shah, N. J. and Li, Fei and
                      Gong, Qiyong},
      title        = {{A} multimodal meta-analysis of regional structural and
                      functional brain alterations in type 2 diabetes},
      journal      = {Frontiers in neuroendocrinology},
      volume       = {62},
      issn         = {0091-3022},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2021-01899},
      pages        = {100915 -},
      year         = {2021},
      abstract     = {Neuroimaging studies have identified brain structural and
                      functional alterations of type 2 diabetes mellitus (T2DM)
                      patients; however, there is no systematic information on the
                      relations between abnormalities in these two domains. We
                      conducted a multimodal meta-analysis of voxel-based
                      morphometry and regional resting-state functional MRI
                      studies in T2DM, including fifteen structural datasets (693
                      patients and 684 controls) and sixteen functional datasets
                      (378 patients and 358 controls). We found, in patients with
                      T2DM compared to controls, conjoint decreased regional gray
                      matter volume (GMV) and altered intrinsic activity mainly in
                      the default mode network including bilateral superior
                      temporal gyrus/Rolandic operculum, left middle and inferior
                      temporal gyrus, and left supramarginal gyrus; decreased GMV
                      alone in the limbic system; and functional abnormalities
                      alone in the cerebellum, insula, and visual cortex. This
                      meta-analysis identified complicated patterns of conjoint
                      and dissociated brain alterations in T2DM patients, which
                      may help provide new insight into the neuropathology of
                      T2DM.},
      cin          = {INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406},
      pnm          = {525 - Decoding Brain Organization and Dysfunction
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-525},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {33862036},
      UT           = {WOS:000701618700009},
      doi          = {10.1016/j.yfrne.2021.100915},
      url          = {https://juser.fz-juelich.de/record/892048},
}