TY  - JOUR
AU  - Holzgreve, Adrien
AU  - Albert, Nathalie L.
AU  - Galldiks, Norbert
AU  - Suchorska, Bogdana
TI  - Use of PET Imaging in Neuro-Oncological Surgery
JO  - Cancers
VL  - 13
IS  - 9
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - FZJ-2021-02030
SP  - 2093 -
PY  - 2021
AB  - This review provides an overview of current applications and perspectives of PET imaging in neuro-oncological surgery. The past and future of PET imaging in the management of patients with glioma and brain metastases are elucidated with an emphasis on amino acid tracers, such as O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET). The thematic scope includes surgical resection planning, prognostication, non-invasive prediction of molecular tumor characteristics, depiction of intratumoral heterogeneity, response assessment, differentiation between tumor progression and treatment-related changes, and emerging new tracers. Furthermore, the role of PET using specific somatostatin receptor ligands for the management of patients with meningioma is discussed. Further advances in neuro-oncological imaging can be expected from promising new techniques, such as hybrid PET/MR scanners and the implementation of artificial intelligence methods, such as radiomics. 
LB  - PUB:(DE-HGF)36 ; PUB:(DE-HGF)16
C6  - 33926002
UR  - <Go to ISI:>//WOS:000649887700001
DO  - DOI:10.3390/cancers13092093
UR  - https://juser.fz-juelich.de/record/892369
ER  -