Review/Journal Article

FZJ-2021-02030

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Use of PET Imaging in Neuro-Oncological Surgery

Holzgreve, A. (Corresponding author) ; Albert, N. L. ; Galldiks, N.FZJ* ; Suchorska, B. (Corresponding author)

2021
MDPI Basel

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Please use a persistent id in citations: http://hdl.handle.net/2128/27732  doi:10.3390/cancers13092093

Abstract: This review provides an overview of current applications and perspectives of PET imaging in neuro-oncological surgery. The past and future of PET imaging in the management of patients with glioma and brain metastases are elucidated with an emphasis on amino acid tracers, such as O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET). The thematic scope includes surgical resection planning, prognostication, non-invasive prediction of molecular tumor characteristics, depiction of intratumoral heterogeneity, response assessment, differentiation between tumor progression and treatment-related changes, and emerging new tracers. Furthermore, the role of PET using specific somatostatin receptor ligands for the management of patients with meningioma is discussed. Further advances in neuro-oncological imaging can be expected from promising new techniques, such as hybrid PET/MR scanners and the implementation of artificial intelligence methods, such as radiomics.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 525 - Decoding Brain Organization and Dysfunction (POF4-525) (POF4-525)

Appears in the scientific report 2021

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