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@ARTICLE{Brmann:892372,
author = {Bärmann, J. and Walter, H. L. and Pikhovych, A. and
Endepols, H. and Fink, G. R. and Rueger, M. A. and
Schroeter, M.},
title = {{A}n analysis of the {C}at{W}alk {XT} and a composite score
to assess neurofunctional deficits after photothrombosis in
mice},
journal = {Neuroscience letters},
volume = {751},
issn = {0304-3940},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2021-02033},
pages = {135811 -},
year = {2021},
abstract = {The purpose of this study was to evaluate CatWalk’s
capability for assessing the functional outcome after
photothrombotic stroke affecting the motor cortex of mice.
Mice were tested up to 21 days after photothrombosis or sham
surgery using CatWalk, and a composite score assessing
functional deficits (neuroscore).The neuroscore demonstrated
deficits of the contralateral forelimb for more than two
weeks after stroke. There were no asymmetric or coordinative
dysfunctions of limbs detected by CatWalk. However, CatWalk
data revealed impairment of locomotion speed and its
depending parameters for one-week after stroke in strong
correlation to the neuroscore.Data suggest that the
composite neuroscore allows to more sensitively and
precisely specify and quantify photothrombosis-induced
hemisyndromes than CatWalk.},
cin = {INM-3 / INM-5},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-5-20090406},
pnm = {525 - Decoding Brain Organization and Dysfunction
(POF4-525)},
pid = {G:(DE-HGF)POF4-525},
typ = {PUB:(DE-HGF)16},
pubmed = {33727129},
UT = {WOS:000635104700002},
doi = {10.1016/j.neulet.2021.135811},
url = {https://juser.fz-juelich.de/record/892372},
}