%0 Journal Article
%A Thiel, Andreas
%A Sauer, Daniel F.
%A Markel, Ulrich
%A Mertens, Stephanie
%A Polen, Tino
%A Schwaneberg, Ulrich
%A Okuda, Jun
%T An artificial ruthenium-containing β-barrel protein for alkene–alkyne coupling reaction
%J Organic & biomolecular chemistry
%V 19
%N 13
%@ 1477-0539
%C Cambridge
%I Royal Society of Chemistry
%M FZJ-2021-03246
%P 2912 - 2916
%D 2021
%Z Biotechnolgie 1    
%X A modified Cp*Ru complex, equipped with a maleimide group, was covalently attached to a cysteine of an engineered variant of Ferric hydroxamate uptake protein component: A (FhuA). This synthetic metalloprotein catalyzed the intermolecular alkene–alkyne coupling of 3-butenol with 5-hexynenitrile. When compared with the protein-free Cp*Ru catalyst, the biohybrid catalyst produced the linear product with higher regioselectivity.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33735355
%U <Go to ISI:>//WOS:000637892000009
%R 10.1039/D1OB00279A
%U https://juser.fz-juelich.de/record/894471