TY  - JOUR
AU  - Thiel, Andreas
AU  - Sauer, Daniel F.
AU  - Markel, Ulrich
AU  - Mertens, Stephanie
AU  - Polen, Tino
AU  - Schwaneberg, Ulrich
AU  - Okuda, Jun
TI  - An artificial ruthenium-containing β-barrel protein for alkene–alkyne coupling reaction
JO  - Organic & biomolecular chemistry
VL  - 19
IS  - 13
SN  - 1477-0539
CY  - Cambridge
PB  - Royal Society of Chemistry
M1  - FZJ-2021-03246
SP  - 2912 - 2916
PY  - 2021
N1  - Biotechnolgie 1    
AB  - A modified Cp*Ru complex, equipped with a maleimide group, was covalently attached to a cysteine of an engineered variant of Ferric hydroxamate uptake protein component: A (FhuA). This synthetic metalloprotein catalyzed the intermolecular alkene–alkyne coupling of 3-butenol with 5-hexynenitrile. When compared with the protein-free Cp*Ru catalyst, the biohybrid catalyst produced the linear product with higher regioselectivity.
LB  - PUB:(DE-HGF)16
C6  - pmid:33735355
UR  - <Go to ISI:>//WOS:000637892000009
DO  - DOI:10.1039/D1OB00279A
UR  - https://juser.fz-juelich.de/record/894471
ER  -