000896716 001__ 896716
000896716 005__ 20220126162549.0
000896716 0247_ $$2doi$$a10.1039/D0CC08226K
000896716 0247_ $$2ISSN$$a0009-241X
000896716 0247_ $$2ISSN$$a0022-4936
000896716 0247_ $$2ISSN$$a1359-7345
000896716 0247_ $$2ISSN$$a1364-548X
000896716 0247_ $$2ISSN$$a2050-5620
000896716 0247_ $$2ISSN$$a2050-5639
000896716 0247_ $$2Handle$$a2128/29752
000896716 0247_ $$2pmid$$a33595019
000896716 0247_ $$2WOS$$aWOS:000627549600019
000896716 037__ $$aFZJ-2021-03549
000896716 041__ $$aEnglish
000896716 082__ $$a540
000896716 1001_ $$0P:(DE-HGF)0$$aBrands, Stefanie$$b0
000896716 245__ $$aUnderstanding substrate binding and the role of gatekeeping residues in PigC access tunnels
000896716 260__ $$aCambridge$$bSoc.$$c2021
000896716 3367_ $$2DRIVER$$aarticle
000896716 3367_ $$2DataCite$$aOutput Types/Journal article
000896716 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1641209648_5797
000896716 3367_ $$2BibTeX$$aARTICLE
000896716 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000896716 3367_ $$00$$2EndNote$$aJournal Article
000896716 520__ $$aSemi-rational redesign of the substrate binding pocket and access tunnels of prodigiosin ligase PigC enhanced the catalytic efficiency in the synthesis of pyrrolic anti-cancer agents more than 45 times. A molecular understanding was gained on residues V333 and T334 relevant to substrate binding and translocation of small pyrroles through PigC access tunnels.
000896716 536__ $$0G:(DE-HGF)POF4-2171$$a2171 - Biological and environmental resources for sustainable use (POF4-217)$$cPOF4-217$$fPOF IV$$x0
000896716 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
000896716 7001_ $$0P:(DE-HGF)0$$aSikkens, Jarno G.$$b1
000896716 7001_ $$0P:(DE-HGF)0$$aDavari, Mehdi D.$$b2
000896716 7001_ $$0P:(DE-Juel1)169140$$aBrass, Hannah$$b3$$ufzj
000896716 7001_ $$0P:(DE-Juel1)157813$$aKlein, Andreas$$b4
000896716 7001_ $$0P:(DE-Juel1)128906$$aPietruszka, Jörg$$b5$$ufzj
000896716 7001_ $$0P:(DE-HGF)0$$aRuff, Anna Joëlle$$b6
000896716 7001_ $$0P:(DE-HGF)0$$aSchwaneberg, Ulrich$$b7$$eCorresponding author
000896716 773__ $$0PERI:(DE-600)1472881-3$$a10.1039/D0CC08226K$$gVol. 57, no. 21, p. 2681 - 2684$$n21$$p2681 - 2684$$tChemical communications$$v57$$x1364-548X$$y2021
000896716 8564_ $$uhttps://juser.fz-juelich.de/record/896716/files/24-Brands-et%20al-Main%20article_revised_.pdf$$yPublished on 2021-02-02. Available in OpenAccess from 2022-02-02.$$zStatID:(DE-HGF)0510
000896716 8564_ $$uhttps://juser.fz-juelich.de/record/896716/files/d0cc08226k.pdf$$yRestricted
000896716 909CO $$ooai:juser.fz-juelich.de:896716$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000896716 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-HGF)0$$aRWTH Aachen$$b0$$kRWTH
000896716 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-HGF)0$$aRWTH Aachen$$b1$$kRWTH
000896716 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-HGF)0$$aRWTH Aachen$$b2$$kRWTH
000896716 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)169140$$aForschungszentrum Jülich$$b3$$kFZJ
000896716 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)169140$$a Heinrich-Heine-Universität Düsseldorf$$b3
000896716 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)157813$$a Heinrich-Heine-Universität Düsseldorf$$b4
000896716 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)128906$$aForschungszentrum Jülich$$b5$$kFZJ
000896716 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)128906$$a Heinrich-Heine-Universität Düsseldorf$$b5
000896716 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-HGF)0$$aRWTH Aachen$$b6$$kRWTH
000896716 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-HGF)0$$aRWTH Aachen$$b7$$kRWTH
000896716 9131_ $$0G:(DE-HGF)POF4-217$$1G:(DE-HGF)POF4-210$$2G:(DE-HGF)POF4-200$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-2171$$aDE-HGF$$bForschungsbereich Erde und Umwelt$$lErde im Wandel – Unsere Zukunft nachhaltig gestalten$$vFür eine nachhaltige Bio-Ökonomie – von Ressourcen zu Produkten$$x0
000896716 9141_ $$y2021
000896716 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0530$$2StatID$$aEmbargoed OpenAccess
000896716 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCHEM COMMUN : 2019$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bCHEM COMMUN : 2019$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)1210$$2StatID$$aDBCoverage$$bIndex Chemicus$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG$$d2021-01-29$$wger
000896716 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)1200$$2StatID$$aDBCoverage$$bChemical Reactions$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0430$$2StatID$$aNational-Konsortium$$d2021-01-29$$wger
000896716 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2021-01-29
000896716 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2021-01-29$$wger
000896716 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2021-01-29
000896716 920__ $$lyes
000896716 9201_ $$0I:(DE-Juel1)IBOC-20090406$$kIBOC$$lInstitut für Bioorganische Chemie (HHUD)$$x0
000896716 9201_ $$0I:(DE-Juel1)IBG-1-20101118$$kIBG-1$$lBiotechnologie$$x1
000896716 980__ $$ajournal
000896716 980__ $$aVDB
000896716 980__ $$aUNRESTRICTED
000896716 980__ $$aI:(DE-Juel1)IBOC-20090406
000896716 980__ $$aI:(DE-Juel1)IBG-1-20101118
000896716 9801_ $$aFullTexts