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@ARTICLE{Kohle:896740,
author = {Kohle, Felix and Sprenger, Alina and Klein, Ines and Fink,
Gereon R. and Lehmann, Helmar C.},
title = {{N}erve conductions studies in experimental models of
autoimmune neuritis: {A} meta-analysis and guideline},
journal = {Journal of neuroimmunology},
volume = {352},
issn = {0165-5728},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2021-03565},
pages = {577470 -},
year = {2021},
note = {Bitte Post-print ergänzen},
abstract = {Nerve conduction studies (NCS) are essential to assess
peripheral nerve fiber function in research models of
immune-mediated neuritis. However, the current lack of
standard protocols and reference values impedes data
comparability across models and studies. We performed a
systematic review and subsequent meta-analysis of the last
30 years of NCS of immune-mediated neuritis in Lewis-rats.
Twenty-six papers met the inclusion criteria for
meta-analysis. Extracted data showed considerable
heterogeneity of recorded nerve conduction velocity (NCV)
and compound muscle action potential (CMAP). Studies also
significantly differed in terms of technical, methodical,
and data reporting issues. The heterogeneity of the
underlying studies emphasizes the need for standardization
when conducting and reporting NCS in rats. We provide
normative values for NCS of the sciatic nerve of Lewis rats
and propose seven items that should be addressed when NCS
are performed when studying immune paradigms in Lewis rats.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {33508768},
UT = {WOS:000640526200009},
doi = {10.1016/j.jneuroim.2020.577470},
url = {https://juser.fz-juelich.de/record/896740},
}