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@ARTICLE{Fehlbaum:897166,
author = {Fehlbaum, Lynn V and Borbás, Réka and Paul, Katharina and
Eickhoff, Simon b and Raschle, Nora},
title = {{E}arly and late neural correlates of mentalizing: {ALE}
meta-analyses in adults, children and adolescents},
journal = {Social cognitive and affective neuroscience},
volume = {17},
number = {4},
issn = {1749-5024},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2021-03656},
pages = {351-366},
year = {2022},
abstract = {The ability to understand mental states of others is
referred to as mentalizing and enabled by our Theory of
Mind. This social skill relies on brain regions comprising
the mentalizing network, as robustly observed in adults, but
also in a growing number of developmental studies. We
summarized and compared neuroimaging evidence in
children/adolescents and adults during mentalizing using
coordinate-based activation likelihood estimation
meta-analyses to inform about brain regions consistently or
differentially engaged across age categories. Adults (N =
5286) recruited medial prefrontal and middle/inferior
frontal cortices, precuneus, temporoparietal junction and
middle temporal gyri during mentalizing, which were
functionally connected to bilateral inferior/superior
parietal lobule and thalamus/striatum. Conjunction and
contrast analyses revealed that children and adolescents (N
= 479) recruit similar, but fewer regions within core
mentalizing regions. Subgroup analyses revealed an early
continuous engagement of middle medial prefrontal cortex,
precuneus and right temporoparietal junction in younger
children (8-11y) and adolescents (12-18y). Adolescents
additionally recruited the left temporoparietal junction and
middle/inferior temporal cortex. Overall, the observed
engagement of the medial prefrontal cortex, precuneus and
right temporoparietal junction during mentalizing across all
ages reflects an early specialization of some key regions of
the social brain.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:34545389},
UT = {WOS:000776757400001},
doi = {10.1093/scan/nsab105},
url = {https://juser.fz-juelich.de/record/897166},
}