TY  - JOUR
AU  - Sorokina, Oksana
AU  - Mclean, Colin
AU  - Croning, Mike D. R.
AU  - Heil, Katharina F.
AU  - Wysocka, Emilia
AU  - He, Xin
AU  - Sterratt, David
AU  - Grant, Seth G. N.
AU  - Simpson, T. Ian
AU  - Armstrong, J. Douglas
TI  - A unified resource and configurable model of the synapse proteome and its role in disease
JO  - Scientific reports
VL  - 11
IS  - 1
SN  - 2045-2322
CY  - [London]
PB  - Macmillan Publishers Limited, part of Springer Nature
M1  - FZJ-2021-06129
SP  - 9967
PY  - 2021
AB  - Genes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. We integrated 58 published synaptic proteomic datasets that describe over 8000 proteins and combined them with direct protein–protein interactions and functional metadata to build a network resource that reveals the shared and unique protein components that underpin multiple disorders. All the data are provided in a flexible and accessible format to encourage custom use.
LB  - PUB:(DE-HGF)16
C6  - pmid:33976238
UR  - <Go to ISI:>//WOS:000658810700001
DO  - DOI:10.1038/s41598-021-88945-7
UR  - https://juser.fz-juelich.de/record/904559
ER  -