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@ARTICLE{Bethlehem:905771,
      author       = {Bethlehem, Richard AI and Seidlitz, Jakob and White, Simon
                      R and Vogel, Jacob W and Anderson, Kevin M and Adamson,
                      Chris and Adler, Sophie and Alexopoulos, George S and
                      Anagnostou, Evdokia and Areces-Gonzalez, Ariosky and Astle,
                      Duncan E and Auyeung, Bonnie and Ayub, Muhammad and Ball,
                      Gareth and Baron-Cohen, Simon and Beare, Richard and
                      Bedford, Saashi A and Benegal, Vivek and Beyer, Frauke and
                      Bae, Jong Bin and Blangero, John and Cabez, Manuel Blesa and
                      Boardman, James P and Borzage, Matthew and Bosch-Bayard,
                      Jorge F and Bourke, Niall and Calhoun, Vince D and
                      Chakravarty, Mallar M and Chen, Christina and Chertavian,
                      Casey and Chetelat, Gael and Chong, Yap S and Cole, James H
                      and Corvin, Aiden and Courchesne, Eric and Crivello, Fabrice
                      and Cropley, Vanessa L and Crosbie, Jennifer and Crossley,
                      Nicolas and Delarue, Marion and Desrivieres, Sylvane and
                      Devenyi, Gabriel and Biase, Maria A Di and Dolan, Ray and
                      Donald, Kirsten A and Donohoe, Gary and Dunlop, Katharine
                      and Edwards, Anthony D and Elison, Jed T and Ellis, Cameron
                      T and Elman, Jeremy A and Eyler, Lisa and Fair, Damien A and
                      Fletcher, Paul C and Fonagy, Peter and Franz, Carol E and
                      Galan-Garcia, Lidice and Gholipour, Ali and Giedd, Jay and
                      Gilmore, John H and Glahn, David C and Goodyer, Ian and
                      Grant, PE and Groenewold, Nynke A and Gunning, Faith M and
                      Gur, Raquel E and Gur, Ruben C and Hammill, Christopher F
                      and Hansson, Oskar and Hedden, Trey and Heinz, Andreas and
                      Henson, Richard and Heuer, Katja and Hoare, Jacqueline and
                      Holla, Bharath and Holmes, Avram J and Holt, Rosie and
                      Huang, Hao and Im, Kiho and Ipser, Jonathan and Jack,
                      Clifford R and Jackowski, Andrea P and Jia, Tianye and
                      Johnson, Keith A and Jones, David T and Jones, Peter B and
                      Kahn, Rene and Karlsson, Hasse and Karlsson, Linnea and
                      Kawashima, Ryuta and Kelley, Elizabeth A and Kern, Silke and
                      Kim, KW and Kitzbichler, Manfred G and Kremen, William S and
                      Lalonde, Francois and Landeau, Brigitte and Lee, Subin and
                      Lerch, Jason and Lewis, John D and Li, Jiao and Liao, Wei
                      and Linares, Deirel P and Liston, Conor and Lombardo,
                      Michael V and Lv, Jinglei and Lynch, Charles and Mallard,
                      Travis T and Marcelis, Machteld and Markello, Ross D and
                      Mazoyer, Bernard and McGuire, Philip and Meaney, Michael J
                      and Mechelli, Andrea and Medic, Nenad and Misic, Bratislav
                      and Morgan, Sarah E and Mothersill, David and Nigg, Joel and
                      Ong, Marcus QW and Ortinau, Cynthia and Ossenkoppele, Rik
                      and Ouyang, Minhui and Palaniyappan, Lena and Paly, Leo and
                      Pan, Pedro M and Pantelis, Christos and Park, Min Tae M and
                      Paus, Tomas and Pausova, Zdenka and Binette, Alexa Pichet
                      and Pierce, Karen and Qian, Xing and Qiu, Anqi and Qiu,
                      Jiang and Raznahan, Armin and Rittman, Timothy and Rollins,
                      Caitlin K and Romero-Garcia, Rafael and Ronan, Lisa and
                      Rosenberg, Monica D and Rowitch, David H and Salum, Giovanni
                      A and Satterthwaite, Theodore D and Schaare, Lina and
                      Schachar, Russell J and Scholl, Michael and Schultz, Aaron P
                      and Schumann, Gunter and Sharp, David},
      title        = {{B}raincharts for the human lifespan},
      reportid     = {FZJ-2022-00994},
      year         = {2021},
      abstract     = {Over the past 25 years, neuroimaging has become a
                      ubiquitous tool in basic research and clinical studies of
                      the human brain. However, there are no reference standards
                      against which to anchor measures of individual differences
                      in brain morphology, in contrast to growth charts for traits
                      such as height and weight. Here, we built an interactive
                      online resource (www.brainchart.io) to quantify individual
                      differences in brain structure from any current or future
                      magnetic resonance imaging (MRI) study, against models of
                      expected age-related trends. With the goal of basing these
                      on the largest and most inclusive dataset, we aggregated MRI
                      data spanning 115 days post-conception through 100 postnatal
                      years, totaling 122,123 scans from 100,071 individuals in
                      over 100 studies across 6 continents. When quantified as
                      centile scores relative to the reference models, individual
                      differences show high validity with non-MRI brain growth
                      estimates and high stability across longitudinal assessment.
                      Centile scores helped identify previously unreported brain
                      developmental milestones and demonstrated increased genetic
                      heritability compared to non-centiled MRI phenotypes.
                      Crucially for the study of brain disorders, centile scores
                      provide a standardised and interpretable measure of
                      deviation that reveals new patterns of neuroanatomical
                      differences across neurological and psychiatric disorders
                      emerging during development and ageing. In sum, brain charts
                      for the human lifespan are an essential first step towards
                      robust, standardised quantification of individual variation
                      and for characterizing deviation from age-related trends.
                      Our global collaborative study …},
      cin          = {INM-7},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)25},
      url          = {https://juser.fz-juelich.de/record/905771},
}