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005     20240313094944.0
037 _ _ |a FZJ-2022-01512
100 1 _ |a van Albada, Sacha
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111 2 _ |a 6th HBP Student Conference on Interdisciplinary Brain Research
|c online
|d 2022-02-22 - 2022-02-24
|w online
245 _ _ |a Multi-scale modeling of resting-state activity in human and non-human primate cortices
260 _ _ |c 2022
336 7 _ |a Conference Paper
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336 7 _ |a Other
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520 _ _ |a To date, models of the cerebral cortex have seldom combined accounts of the dynamics in local cortical circuits with large-scale activity patterns across multiple areas. I will present supercomputational simulation studies of resting-state activity in macaque and human cerebral cortices which bring together microscopic and macroscopic descriptions of the structure and dynamics. The simulations reproduce key aspects of spiking statistics as well as patterns of fMRI functional connectivity, and support the notion that cerebral cortex is poised just below a state transition. The models can serve as platforms for testing theories of cortical function in a setting constrained by anatomical and physiological data at multiple scales.
536 _ _ |a 5231 - Neuroscientific Foundations (POF4-523)
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536 _ _ |a 5235 - Digitization of Neuroscience and User-Community Building (POF4-523)
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536 _ _ |a HBP SGA3 - Human Brain Project Specific Grant Agreement 3 (945539)
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536 _ _ |a DFG project 347572269 - Heterogenität von Zytoarchitektur, Chemoarchitektur und Konnektivität in einem großskaligen Computermodell der menschlichen Großhirnrinde (347572269)
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536 _ _ |a Brain-Scale Simulations (jinb33_20191101)
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536 _ _ |a Brain-Scale Simulations (jinb33_20121101)
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536 _ _ |a SPP 2041 347572269 - Integration von Multiskalen-Konnektivität und Gehirnarchitektur in einem supercomputergestützten Modell der menschlichen Großhirnrinde (347572269)
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536 _ _ |a HBP SGA2 - Human Brain Project Specific Grant Agreement 2 (785907)
|0 G:(EU-Grant)785907
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|f H2020-SGA-FETFLAG-HBP-2017
536 _ _ |a Brain-Scale Simulations (jinb33_20220812)
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910 1 _ |a Forschungszentrum Jülich
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