000009077 001__ 9077
000009077 005__ 20210129210455.0
000009077 0247_ $$2pmid$$apmid:20117896
000009077 0247_ $$2DOI$$a10.1016/j.mri.2009.11.006
000009077 0247_ $$2WOS$$aWOS:000276042400004
000009077 037__ $$aPreJuSER-9077
000009077 041__ $$aeng
000009077 082__ $$a610
000009077 084__ $$2WoS$$aRadiology, Nuclear Medicine & Medical Imaging
000009077 1001_ $$0P:(DE-Juel1)VDB65642$$aOros-Peusquens, A.M.$$b0$$uFZJ
000009077 245__ $$aIn vivo imaging of the human brain at 1.5 T with 0,6-mm isotropic resolution
000009077 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2010
000009077 300__ $$a329 - 340
000009077 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000009077 3367_ $$2DataCite$$aOutput Types/Journal article
000009077 3367_ $$00$$2EndNote$$aJournal Article
000009077 3367_ $$2BibTeX$$aARTICLE
000009077 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000009077 3367_ $$2DRIVER$$aarticle
000009077 440_0 $$04146$$aMagnetic Resonance Imaging$$v28$$x0730-725X
000009077 500__ $$aWe are grateful to the volunteers for their collaboration. The MRI facility is supported by the Bundesministerium far Bildung und Forschung (BMBF) through a grant (BMBF 01GO0104) to N.J.S. and K.Z. This Human Brain Project/Neuroinformatics research is funded by the National Institute of Biomedical Imaging and Bioengineering, the National Institute of Neurological Disorders and Stroke and the National Institute of Mental Health. The support of the BMBF (Brain Imaging Centre West BMBF, 01GO0204) is kindly acknowledged.
000009077 520__ $$aWe present high-resolution in vivo anatomical scans with 3D whole-brain coverage and an isotropic resolution of 0.6 mm, obtained at a clinical field of 1.5 T. The data are acquired in 10 independent scans over two sessions using a 3D magnetization-prepared, gradient echo sequence, modified to output phase images in addition to magnitude images. The independent scans are coregistered to correct for head motion, prior to performing complex averaging. The resolution of the final, averaged image, is found to be equal to the nominal one. The separation between the distribution of gray-scale values characterizing the gray and white matter, respectively, is substantially improved over single-scan images. Complex and magnitude averaging are compared and found to deliver similar results for regions with a high initial signal-to-noise ratio (SNR) within the brain. However, complex averaging is strongly recommended for quantitative applications or for studies where regions of low initial SNR are important. To summarize, a method for high-resolution in vivo anatomical imaging at a clinical field strength is demonstrated and is recommended for brain mapping. The method can also be applied at higher fields with a reduced acquisition time.
000009077 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
000009077 536__ $$0G:(DE-HGF)POF2-89573$$a89573 - Neuroimaging (POF2-89573)$$cPOF2-89573$$fPOF II T$$x1
000009077 588__ $$aDataset connected to Web of Science, Pubmed
000009077 65320 $$2Author$$aHigh-resolution MRI
000009077 65320 $$2Author$$a1.5 T
000009077 65320 $$2Author$$aCoregistration
000009077 65320 $$2Author$$aAveraging
000009077 65320 $$2Author$$aComplex averaging
000009077 65320 $$2Author$$aIn vivo anatomical imaging
000009077 65320 $$2Author$$aBrain imaging
000009077 65320 $$2Author$$aVolume coverage
000009077 65320 $$2Author$$a0.6-mm isotropic resolution
000009077 650_2 $$2MeSH$$aAdult
000009077 650_2 $$2MeSH$$aAlgorithms
000009077 650_2 $$2MeSH$$aAnisotropy
000009077 650_2 $$2MeSH$$aFemale
000009077 650_2 $$2MeSH$$aHumans
000009077 650_2 $$2MeSH$$aImage Enhancement: methods
000009077 650_2 $$2MeSH$$aImage Interpretation, Computer-Assisted: methods
000009077 650_2 $$2MeSH$$aImaging, Three-Dimensional: methods
000009077 650_2 $$2MeSH$$aMagnetic Resonance Imaging: methods
000009077 650_2 $$2MeSH$$aMale
000009077 650_2 $$2MeSH$$aReproducibility of Results
000009077 650_2 $$2MeSH$$aSensitivity and Specificity
000009077 650_7 $$2WoSType$$aJ
000009077 7001_ $$0P:(DE-Juel1)VDB30236$$aStoecker, T.$$b1$$uFZJ
000009077 7001_ $$0P:(DE-Juel1)131631$$aAmunts, K.$$b2$$uFZJ
000009077 7001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b3$$uFZJ
000009077 7001_ $$0P:(DE-Juel1)131794$$aShah, J. N.$$b4$$uFZJ
000009077 773__ $$0PERI:(DE-600)1500646-3$$a10.1016/j.mri.2009.11.006$$gVol. 28, p. 329 - 340$$p329 - 340$$q28<329 - 340$$tMagnetic resonance imaging$$v28$$x0730-725X$$y2010
000009077 8567_ $$uhttp://dx.doi.org/10.1016/j.mri.2009.11.006
000009077 909CO $$ooai:juser.fz-juelich.de:9077$$pVDB
000009077 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000009077 9141_ $$y2010
000009077 9132_ $$0G:(DE-HGF)POF3-573$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vNeuroimaging$$x0
000009077 9131_ $$0G:(DE-HGF)POF2-89573$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vNeuroimaging$$x1
000009077 9201_ $$0I:(DE-Juel1)INM-2-20090406$$gINM$$kINM-2$$lMolekulare Organisation des Gehirns$$x0
000009077 9201_ $$0I:(DE-Juel1)INM-1-20090406$$gINM$$kINM-1$$lStrukturelle und funktionelle Organisation des Gehirns$$x1
000009077 9201_ $$0I:(DE-Juel1)INM-4-20090406$$gINM$$kINM-4$$lPhysik der Medizinischen Bildgebung$$x2
000009077 970__ $$aVDB:(DE-Juel1)118480
000009077 980__ $$aVDB
000009077 980__ $$aConvertedRecord
000009077 980__ $$ajournal
000009077 980__ $$aI:(DE-Juel1)INM-2-20090406
000009077 980__ $$aI:(DE-Juel1)INM-1-20090406
000009077 980__ $$aI:(DE-Juel1)INM-4-20090406
000009077 980__ $$aUNRESTRICTED
000009077 981__ $$aI:(DE-Juel1)INM-1-20090406
000009077 981__ $$aI:(DE-Juel1)INM-4-20090406