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@ARTICLE{OrosPeusquens:9077,
author = {Oros-Peusquens, A.M. and Stoecker, T. and Amunts, K. and
Zilles, K. and Shah, J. N.},
title = {{I}n vivo imaging of the human brain at 1.5 {T} with 0,6-mm
isotropic resolution},
journal = {Magnetic resonance imaging},
volume = {28},
issn = {0730-725X},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {PreJuSER-9077},
pages = {329 - 340},
year = {2010},
note = {We are grateful to the volunteers for their collaboration.
The MRI facility is supported by the Bundesministerium far
Bildung und Forschung (BMBF) through a grant (BMBF 01GO0104)
to N.J.S. and K.Z. This Human Brain Project/Neuroinformatics
research is funded by the National Institute of Biomedical
Imaging and Bioengineering, the National Institute of
Neurological Disorders and Stroke and the National Institute
of Mental Health. The support of the BMBF (Brain Imaging
Centre West BMBF, 01GO0204) is kindly acknowledged.},
abstract = {We present high-resolution in vivo anatomical scans with 3D
whole-brain coverage and an isotropic resolution of 0.6 mm,
obtained at a clinical field of 1.5 T. The data are acquired
in 10 independent scans over two sessions using a 3D
magnetization-prepared, gradient echo sequence, modified to
output phase images in addition to magnitude images. The
independent scans are coregistered to correct for head
motion, prior to performing complex averaging. The
resolution of the final, averaged image, is found to be
equal to the nominal one. The separation between the
distribution of gray-scale values characterizing the gray
and white matter, respectively, is substantially improved
over single-scan images. Complex and magnitude averaging are
compared and found to deliver similar results for regions
with a high initial signal-to-noise ratio (SNR) within the
brain. However, complex averaging is strongly recommended
for quantitative applications or for studies where regions
of low initial SNR are important. To summarize, a method for
high-resolution in vivo anatomical imaging at a clinical
field strength is demonstrated and is recommended for brain
mapping. The method can also be applied at higher fields
with a reduced acquisition time.},
keywords = {Adult / Algorithms / Anisotropy / Female / Humans / Image
Enhancement: methods / Image Interpretation,
Computer-Assisted: methods / Imaging, Three-Dimensional:
methods / Magnetic Resonance Imaging: methods / Male /
Reproducibility of Results / Sensitivity and Specificity / J
(WoSType)},
cin = {INM-2 / INM-1 / INM-4},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-1-20090406 /
I:(DE-Juel1)INM-4-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89573 - Neuroimaging (POF2-89573)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89573},
shelfmark = {Radiology, Nuclear Medicine $\&$ Medical Imaging},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:20117896},
UT = {WOS:000276042400004},
doi = {10.1016/j.mri.2009.11.006},
url = {https://juser.fz-juelich.de/record/9077},
}