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@ARTICLE{Galldiks:912547,
author = {Galldiks, Norbert and Lohmann, Philipp},
title = {{I}maging patterns in patients with newly diagnosed
glioblastoma in {E}ngland},
journal = {Neuro-oncology practice},
volume = {9},
number = {6},
issn = {2054-2577},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2022-05720},
pages = {461 - 462},
year = {2022},
abstract = {The study by Dumba and colleagues1 explored the incidence
and timing of various peridiagnostic neuroimaging techniques
such as MRI, CT, and PET in patients with newly diagnosed
glioblastoma using a national database. Particularly,
preoperative, early postoperative, and pre-radiotherapy
imaging patterns for all glioblastoma patients aged 15–99
years resident in England in the years 2013 and 2014 were
retrospectively evaluated.The entire cohort for data
analysis comprised 4,307 patients. The main finding of the
study is that prediagnostic imaging appears uniform, whereas
postdiagnostic imaging practice varied considerably. Of
note, the authors observed that there is clear evidence for
low use of early postoperative MRI, the low use of
additional MR imaging before radiotherapy, and the very
limited use of other neuroimaging techniques such as
advanced MRI and PET. For example, in the group of patients
who underwent surgery and chemoradiation, only $51\%$ had an
early postoperative MRI within 72 hours after surgery. In
patients undergoing surgery who subsequently received
radiotherapy, only $61\%$ had both an early postoperative
and a pre-radiotherapy MRI. To improve the diagnostic
performance, only $7\%$ of the cohort underwent one or more
of the advanced MRI options (ie, perfusion-weighted MRI,
proton MR spectroscopy), and less than $1\%$ of the cohort
had additional PET imaging with various tracers (eg,
radiolabeled amino acids, [18F]-2-fluoro-2-deoxy-D-glucose)
during the course of the disease.},
cin = {INM-3 / INM-4},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
pnm = {5252 - Brain Dysfunction and Plasticity (POF4-525)},
pid = {G:(DE-HGF)POF4-5252},
typ = {PUB:(DE-HGF)16},
pubmed = {36388412},
UT = {WOS:000885427200002},
doi = {10.1093/nop/npac059},
url = {https://juser.fz-juelich.de/record/912547},
}