Open Access

Spiking neural networks mimic the way the human brain processes data and excel in efficiency. With the advent of the memristor, foundations are laid for scalable and low-power integrated electronic implementations. [...]

Chiplet-based processor design, which combines small dies called chiplets to form a larger chip, enables scalable designs at economical costs. This trend has received high attention such that standards for chiplet design have rapidly established, including packaging, protocols, and Chiplet-to-Chiplet (C2C) interfaces. [...]

Earth system models (ESMs) allow numerical simulations of the Earth's climate system. Driven by the need to better understand climate change and its impacts, these models have become increasingly sophisticated over time, generating vast amounts of data. [...]

Apraxia is a common symptom in Alzheimer's disease (AD) that reduces autonomy and quality of life. However, the neural basis underlying apraxia in AD, for example, reflected by functional connectivity (FC) alterations, remains unexplored. [...]

Background: Apraxia is a motor-cognitive disorder that primary sensorimotor deficits cannot solely explain. Previous research in stroke patients has focused on damage to the fronto-parietal praxis networks in the left hemisphere (LH) as the cause of apraxic deficits [...]

A focal ischemic lesion is thought to alter neuronal activity beyond the area of structural damage, thereby interfering with the whole network architecture. Here, we used a combination of transcranial magnetic stimulation and electroencephalography in conjunction with dynamic connectivity analyses and graph theory to study alterations and reorganization of cortical connectivity in a cohort of 41 patients longitudinally after stroke. [...]

In Alzheimer's disease (AD), limbic non-AD co-pathologies are common and contribute to memory impairment and accelerated clinical progression. To date, in vivo biomarkers of these co-pathologies are lacking. [...]

Zusammenfassung: Zusammenfassung. Anhand einer Stichprobe von 524 gesunden Probanden wurden alters- und bildungsabhängige Normen für den Kognitionsgesamtwert des Kölner Neuropsychologischen Screenings für Schlaganfallpatienten (KöpSS) erstellt. [...]