Open Access

Letzte Einträge:
2018-09-18
11:03
OpenAccess [FZJ-2018-05368] Journal Article
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Age at first birth in women is genetically associated with increased risk of schizophrenia
Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). [...]
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2018-09-18
10:58
OpenAccess [FZJ-2018-05367] Journal Article
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Unilateral Botulinum Neurotoxin-A Injection into the Striatum of C57BL/6 Mice Leads to a Different Motor Behavior Compared with Rats
Toxins 10(7), 295 () [10.3390/toxins10070295]
Different morphological changes in the caudate-putamen (CPu) of naïve rats and mice were observed after intrastriatal botulinum neurotoxin-A (BoNT-A) injection. For this purpose we here studied various motor behaviors in mice (n = 46) longitudinally up to 9 months after intrastriatal BoNT-A administration as previously reported for rats, and compared both outcomes [...]
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2018-09-17
12:05
OpenAccess [FZJ-2018-05354] Journal Article
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Acetylcholine Neurotransmitter Receptor Densities in the Striatum of Hemiparkinsonian Rats Following Botulinum Neurotoxin-A Injection
Cholinergic neurotransmission has a pivotal function in the caudate-putamen, and is highly associated with the pathophysiology of Parkinson's disease. Here, we investigated long-term changes in the densities of the muscarinic receptor subtypes M1, M2, M3 (mAchRs) and the nicotinic receptor subtype α4β2 (nAchRs) in the striatum of the 6-OHDA-induced hemiparkinsonian (hemi-PD) rat model using quantitative in vitro receptor autoradiography. [...]
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2018-09-17
11:14
OpenAccess [FZJ-2018-05352] Journal Article
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Mapping of M2 and 5-HT1A Receptors in the Human Amygdala
Subdivisions of the amygdala were identified in thecolor-coded receptor autoradiographs immediately adjacentto Nissl-stained sections in the right hemisphere atthe level of the central nucleus. Color scales visualize theconcentrations for each receptor (cholinergic muscarinicM2 or serotoninergic 5-HT1A receptors)..
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2018-09-13
08:42
OpenAccess [FZJ-2018-05287] Journal Article
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Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum
Superconducting high kinetic inductance elements constitute a valuable resource for quantum circuit design and millimeter-wave detection. Granular aluminum (grAl) in the superconducting regime is a particularly interesting material since it has already shown a kinetic inductance in the range of nH/□ and its deposition is compatible with conventional Al/AlOx/Al Josephson junction fabrication. [...]
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2018-09-12
17:48
OpenAccess [FZJ-2018-05285] Journal Article
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Precision Measurement of Cosmic-Ray Nitrogen and its Primary and Secondary Components with the Alpha Magnetic Spectrometer on the International Space Station
A precision measurement of the nitrogen flux with rigidity (momentum per unit charge) from 2.2 GV to 3.3 TV based on 2.2×106 events is presented. The detailed rigidity dependence of the nitrogen flux spectral index is presented for the first time. [...]
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2018-09-12
17:42
OpenAccess [FZJ-2018-05284] Journal Article
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Observation of Complex Time Structures in the Cosmic-Ray Electron and Positron Fluxes with the Alpha Magnetic Spectrometer on the International Space Station
We present high-statistics, precision measurements of the detailed time and energy dependence of the primary cosmic-ray electron flux and positron flux over 79 Bartels rotations from May 2011 to May 2017 in the energy range from 1 to 50 GeV. For the first time, the charge-sign dependent modulation during solar maximum has been investigated in detail by leptons alone. [...]
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2018-09-12
17:36
OpenAccess [FZJ-2018-05283] Journal Article
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Observation of Fine Time Structures in the Cosmic Proton and Helium Fluxes with the Alpha Magnetic Spectrometer on the International Space Station13
We present the precision measurement from May 2011 to May 2017 (79 Bartels rotations) of the proton fluxes at rigidities from 1 to 60 GV and the helium fluxes from 1.9 to 60 GV based on a total of 1×109 events collected with the Alpha Magnetic Spectrometer aboard the International Space Station. This measurement is in solar cycle 24, which has the solar maximum in April 2014. [...]
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2018-09-12
09:16
OpenAccess [FZJ-2018-05277] Book/Dissertation / PhD Thesis

Laser Treatment of Silicon Thin-Films for Photovoltaic Applications
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Energie & Umwelt / Energy & Environment 432, vii, 165 () = Dissertation, RWTH Aachen University, 2018
Thin-film silicon is an important material in the fields of photovoltaics. As wellas microcrystalline (μc-Si:H), amorphous (a-Si:H) silicon has been used for a longas an absorber in thin-film solar cells. [...]
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2018-09-11
14:36
OpenAccess [FZJ-2018-05266] Journal Article
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Predicting IDH genotype in gliomas using FET PET radiomics
Mutations in the isocitrate dehydrogenase (IDH mut) gene have gained paramount importance for the prognosis of glioma patients. To date, reliable techniques for a preoperative evaluation of IDH genotype remain scarce. [...]
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