Journal Article

FZJ-2026-01131

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png The roles of impulsivity, comorbid ADHD, and borderline personality disorder in patients with bulimia nervosa

Gilsbach, S. (Corresponding author) ; Leuchtenberger, J. ; Herpertz-Dahlmann, B. ; Voderholzer, U. ; Konrad, K.FZJ* ; von Polier, G.FZJ* ; Seitz, J. ; Fichter, M.

2025
Springer International Publ. Cham

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Please use a persistent id in citations: doi:10.1007/s40519-025-01713-8  doi:10.34734/FZJ-2026-01131

Abstract: BackgroundBulimia nervosa (BN) is a serious mental illness with impulsivity as a cardinal symptom. Impulsivity contributes to various other, often comorbid, mental disorders, such as attention deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD). The aim of this study was to explore comorbidities of BN with ADHD and BPD as well as the contribution of impulsivity as an underlying trait linking these disorders.MethodsHundred and fifteen females with BN and 98 healthy matched controls (HC) (age range between 16 and 48 years) were assessed regarding adult and childhood-ADHD, personality disorders and impulsivity.ResultsPatients with BN were more impulsive (p < 0.001) and more often fulfilled criteria of childhood/adulthood ADHD (p < 0.001) than HC, and criteria of BPD than expected in the general population. Childhood-ADHD (p = 0.009) and BPD (p = 0.017) both were significant positive predictors for impulsivity scores found in patients with BN.ConclusionComorbidity with ADHD and BPD often is prevalent in BN and associated with an increase in impulsivity, the latter being a relevant transdiagnostic trait. It might be beneficial to explore impulsivity as well as comorbidities in the clinical care of patients with BN.Level of evidence IIIEvidence obtained from well-designed cohort or case–control analytic studies.

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Contributing Institute(s):

1. Gehirn & Verhalten (INM-7)
2. Jara-Institut Quantum Information (INM-11)

Research Program(s):

1. 5251 - Multilevel Brain Organization and Variability (POF4-525) (POF4-525)

Appears in the scientific report 2025; 2025

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Database coverage:
; ; ; ; Article Processing Charges ; Clarivate Analytics Master Journal List ; DEAL Springer ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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