Abstract

FZJ-2026-05188

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Web-based tractogram observer for inspection and virtual tract-tracing.

Bakker, R. (Corresponding author)FZJ* ; Sapkal, G. ; van Albada, S.FZJ*

2026

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Please use a persistent id in citations: doi:10.34734/FZJ-2026-05188

Abstract: Comparisons between Diffusion-Weighted-Imaging (DWI)-derived tractograms and tract-tracing studies in macaque typically measure overlap between connectivity matrices at the brain area level. A more in depth comparison between tracer injections and DWI-derived streamlines will yield better insights in tractogram accuracy. We present a new web-app (https://tractogram.observer) that takes a tractogram and anatomical brain image as input and displays all streamlines that start/end within a spherical probe. As an example we take Case 13 from the seminal tract-tracing study by Markov et al. 2012. Tractogram.observer was used to select a probe location that matches the tracer injection location and to show streamline endpoints in slices that best match the published sections. The tool facilitates the comparison between DWI-derived tractograms andtract-tracing experiments, without the need to parcellate the brain. More tractograms and case studies are in preparation.

Keyword(s): Health and Life (1st) ; Biology (2nd)

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Contributing Institute(s):

1. Computational and Systems Neuroscience (IAS-6)

Research Program(s):

1. 5231 - Neuroscientific Foundations (POF4-523) (POF4-523)

Appears in the scientific report 2026

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Database coverage:

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