Journal Article

PreJuSER-12405

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Combining independent drug classes into superior, synergistically acting hybrid molecules

Müller-Schiffmann, A. ; März-Berberich, J.FZJ* ; Andrjevna, A. ; Rönicke, R. ; Bartnik, D.FZJ* ; Brener, O.FZJ* ; Kutzsche, J.FZJ* ; Horn, A. H. C. ; Hellmert, M. ; Gottmann, K. ; Reymann, K. ; Funke, S. A.FZJ* ; Nagel-Steger, L.FZJ* ; Moriscot, C. ; Schoehn, G. ; Sticht, H. ; Willbold, D.FZJ* ; Schrader, T.FZJ* ; Korth, C.

2010
Wiley-VCH Weinheim

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Please use a persistent id in citations: doi:10.1002/anie.201004437

Keyword(s): Amino Acid Sequence (MeSH) ; Amyloid beta-Peptides: chemistry (MeSH) ; Animals (MeSH) ; CHO Cells (MeSH) ; Cricetinae (MeSH) ; Cricetulus (MeSH) ; Drug Design (MeSH) ; Humans (MeSH) ; Immunoprecipitation (MeSH) ; Oligopeptides: chemistry (MeSH) ; Oligopeptides: pharmacology (MeSH) ; Protein Structure, Secondary (MeSH) ; Pyrazoles: chemistry (MeSH) ; Stereoisomerism (MeSH) ; Amyloid beta-Peptides ; D3 peptide ; Oligopeptides ; Pyrazoles ; trimer-TEG-D3 ; J ; aggregation (auto) ; amyloid beta peptides (auto) ; drug design (auto) ; molecular recognition (auto) ; peptides (auto)

Note: The major support for this work was from a grant of the Volkswagen-Stiftung to C. K., T. S., D. W., and H. S. (I/82 649); further funding was provided by EU-FP6 (cNEUPRO), EU-FP7 (PRIORITY) grants to C. K. and a DFG-GRK1033 grant to J.K. and C. K.

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Contributing Institute(s):

1. Strukturbiochemie (ISB-3)

Research Program(s):

1. Funktion und Dysfunktion des Nervensystems (P33)
2. BioSoft: Makromolekulare Systeme und biologische Informationsverarbeitung (P45)

Appears in the scientific report 2010
Notes: Angew Chem Int Ed Engl 2010 Nov.8; 49(46): 8743-6

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Database coverage:
; JCR ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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