BIODIFF: First installations anddetector concepts

Schrader, Tobias; Ostermann, Andreas; Richter, Dieter; Monkenbusch, Michael; Petry, Winfried; Jüttner, Philipp; Laatsch, Bernhard

Internal Report

FZJ-2014-00950

BIODIFF: First installations anddetector concepts

Schrader, T. (Corresponding author)FZJ* ; Ostermann, A. ; Laatsch, B.ZEA-1* ; Jüttner, P. ; Monkenbusch, M.FZJ* ; Petry, W. ; Richter, D.FZJ*

2010

2 pp. (2010)

Please use a persistent id in citations: http://hdl.handle.net/2128/5884

Abstract: In collaboration between the ForschungszentrumJülich (FZJ) and the ForschungsneutronenquelleHeinz Maier-Leibnitz (FRM II) a single crystaldiffractometer optimised for crystals with largeunit cells is being built. Its scientiﬁc focus will bethe determination of the exact location and bond-ing properties of hydrogen atoms in protein orDNA crystals. With this information the hydrationpattern of proteins can be studied, the protona-tion state of critical amino acid side chains canbe determined and even dynamical informationcan be obtained by determining the hydrogen-deuterium exchange of the protein backbone. Inorder to achieve these results two detector con-cepts are foreseen: a) an image plate detectorcovering a large solid angle and b) a neutronscintillator imaged onto a CCD-camera providinga fast read out for a timely alignment of the crys-tals and additional detection abilities.

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Appears in the scientific report 2013

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