Journal Article

PreJuSER-46842

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Autocatalytic polymerization generates persistent random walk of crawling cells

Sambeth, R.FZJ* ; Baumgärtner, A.FZJ*

2001
APS College Park, Md.

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Please use a persistent id in citations: http://hdl.handle.net/2128/1544  doi:10.1103/PhysRevLett.86.5196

Abstract: The autocatalytic polymerization kinetics of the cytoskeletal actin network provides the basic mechanism for a persistent random walk of a crawling cell. It is shown that network remodeling by branching processes near the cell membrane is essential for the bimodal spatial stability of the network which induces a spontaneous breaking of isotropic cell motion. Details of the phenomena are analyzed using a simple polymerization model studied by analytical and simulation methods.

Keyword(s): J

Note: Record converted from VDB: 12.11.2012

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Contributing Institute(s):

1. Theorie II (IFF-TH-II)

Research Program(s):

1. Polymere, Membranen und komplexe Flüssigkeiten (23.30.0)

Appears in the scientific report 2001
Notes: This version is available at the following Publisher URL: http://prl.aps.org

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Database coverage:

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