Journal Article

FZJ-2016-05716

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Positively charged supported lipid bilayer formation on gold surfaces for neuronal cell culture

Choi, S.-E.FZJ* ; Greben, K. ; Wördenweber, R.FZJ* ; Offenhäusser, A. (Corresponding author)FZJ*

2016
AIP Melville, NY

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Please use a persistent id in citations: http://hdl.handle.net/2128/18155  doi:10.1116/1.4945306

Abstract: Supported lipid bilayers are widely used as cell membrane models and sensor platforms, but the usage on goldsurface needs additional surface modification or optimized experimental conditions. In this work, the authors show lipid bilayer formation on plasma activated goldsurfaces in physiological conditions without any other modification if at least 30% positively charged lipids are present. Details of bilayer formation from small unilamellar vesicles were monitored using quartz crystal microbalance with dissipation in both basic and acidic environment. The authors also confirmed that this positively charged bilayer system can sustain primary cortical neuron growth and lipid transfer. This method will provide simple means to construct biomimetic interface on gold electrodes.

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Contributing Institute(s):

1. Bioelektronik (PGI-8)
2. Bioelektronik (ICS-8)
3. JARA-FIT (JARA-FIT)

Research Program(s):

1. 552 - Engineering Cell Function (POF3-552) (POF3-552)

Appears in the scientific report 2016

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Database coverage:
; ; BIOSIS Previews ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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