Journal Article

FZJ-2017-04112

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Expression and purification of an engineered human endothelin receptor B in a monomeric form

Mishin, A. V. (Corresponding author) ; Luginina, A. P. ; Potapenko, A. P. ; Borshchevskiy, V. ; Katritch, V. ; Edelweiss, E. ; Okhrimenko, I. S. ; Gordeliy, V.FZJ* ; Cherezov, V. G.

2016
Springer Science & Business Media B.V. Dordrecht []

This record in other databases:      

Please use a persistent id in citations: doi:10.1134/S1607672916020216

Abstract: In humans, two endothelin receptors, ETa and ETb, are activated by three endogenous 21-mer cyclic peptides, ET-1, ET-2, and ET-3, which control various physiological processes, including vasoconstriction, vasodilation, and stimulation of cell proliferation. The first stage of this study it to produce a stable solubilized and purified receptor in a monodisperse state. This article is focused on the engineering, expression, purification, and characterization of the endothelin receptor B for subsequent structural and functional studies.

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Contributing Institute(s):

1. Strukturbiochemie (ICS-6)

Research Program(s):

1. 551 - Functional Macromolecules and Complexes (POF3-551) (POF3-551)

Appears in the scientific report 2017

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Database coverage:
; Ebsco Academic Search ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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