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@ARTICLE{Abdollahzadeh:837136,
      author       = {Abdollahzadeh, Iman and Schwarten, Melanie and Gensch,
                      Thomas and Willbold, Dieter and Weiergräber, Oliver H.},
      title        = {{T}he {A}tg8 {F}amily of {P}roteins—{M}odulating {S}hape
                      and {F}unctionality of {A}utophagic {M}embranes},
      journal      = {Frontiers in genetics},
      volume       = {8},
      issn         = {1664-8021},
      address      = {Lausanne},
      publisher    = {Frontiers Media},
      reportid     = {FZJ-2017-06125},
      pages        = {109},
      year         = {2017},
      abstract     = {Aging is a multifactorial process involving an accumulation
                      of alterations on various organizational levels, which
                      finally compromises viability and limits the lifespan of
                      organisms. It is now well-established that many aspects of
                      aging can be positively affected by (macro)autophagy, a
                      mechanism of self-digestion found in virtually all
                      eukaryotic cells. A comprehensive understanding of autophagy
                      is thus expected to not only deepen our insight into the
                      mechanisms of aging but to also open up new avenues toward
                      increasing the healthy lifespan in humans. In this review,
                      we focus on the Atg8 family of ubiquitin-like proteins,
                      which play a crucial role in the autophagy process by virtue
                      of their unique mode of reversible membrane association.},
      cin          = {ICS-6 / ICS-4},
      ddc          = {570},
      cid          = {I:(DE-Juel1)ICS-6-20110106 / I:(DE-Juel1)ICS-4-20110106},
      pnm          = {552 - Engineering Cell Function (POF3-552)},
      pid          = {G:(DE-HGF)POF3-552},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000408342900001},
      pubmed       = {pmid:28894458},
      doi          = {10.3389/fgene.2017.00109},
      url          = {https://juser.fz-juelich.de/record/837136},
}