Journal Article FZJ-2018-00136

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Optische Genregulation in Mikrobioreaktoren

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2017
Spektrum Heidelberg

Biospektrum 23(6), 643-645 () [10.1007/s12268-017-0850-0]

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Abstract: Photolabile-caged effector molecules allow non-invasive regulation of gene expression using cell-compatible UVA-irradiation. Based on this method, independent photoregulation of gene expression was combined with optical online monitoring of important cultivation parameters in a 48-well plate format. Thereby, an innovative screening system was created which allows for cost-effective and easily automated expression profiling as well as closed-loop process control.

Classification:

Contributing Institute(s):
  1. Institut für Bioorganische Chemie (HHUD) (IBOC)
  2. Biotechnologie (IBG-1)
Research Program(s):
  1. 581 - Biotechnology (POF3-581) (POF3-581)

Appears in the scientific report 2017
Database coverage:
NCBI Molecular Biology Database ; SCOPUS
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