Journal Article

FZJ-2019-01524

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Single-Molecule Techniques and Cell-Free Protein Synthesis: A Perfect Marriage

Katranidis, A. (Corresponding author)FZJ* ; Fitter, J. (Corresponding author)FZJ*

2019
American Chemical Society Columbus, Ohio

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Please use a persistent id in citations: http://hdl.handle.net/2128/21658  doi:10.1021/acs.analchem.8b03855

Abstract: Single-molecule techniques are nowadays an essential tool to study conformational changes as well as synthesis and folding of proteins. However, preparation of suitable protein samples is often time consuming and demanding. The rapid development of cell-free protein synthesis over the last years opened new perspectives for fast and easy sample preparation but this was not fully exploited until now. Here, we take a look at the advancements in sample preparation as well as in the development of technical approaches and analytical tools, which unavoidably lead to the combination of single-molecule techniques and cell-free protein synthesis. It’s an ideal combination that can unlock the full potential of studying complex biological processes in the near future.

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Contributing Institute(s):

1. Molekulare Biophysik (ICS-5)

Research Program(s):

1. 551 - Functional Macromolecules and Complexes (POF3-551) (POF3-551)

Appears in the scientific report 2019

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Database coverage:
; ; ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; Ebsco Academic Search ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Web of Science Core Collection

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