Journal Article

FZJ-2019-06626

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Mapping dopamine with positron emission tomography: A note of caution

Dagher, A. (Corresponding author) ; Palomero-Gallagher, N.FZJ*

2020
Academic Press Orlando, Fla.

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Please use a persistent id in citations: http://hdl.handle.net/2128/24118  doi:10.1016/j.neuroimage.2019.116203

Abstract: Positron emission tomography (PET) imaging is uniquely suited to measuring neurotransmitter signaling in the human brain. PET tracers for neurotransmitter studies are ligands of the receptor or enzyme of interest labelled with positron emitting isotopes, usually 11C of 18F. By far the most frequent target of PET neurotransmitter imaging is dopamine, and the most commonly used tracer is [11C]raclopride, an antagonist of the dopamine D2 receptor (D2R), first developed by researchers at the Karolinska Institute (Farde et al., 1986).

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Contributing Institute(s):

1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)

Research Program(s):

1. 571 - Connectivity and Activity (POF3-571) (POF3-571)

Appears in the scientific report 2020

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