Journal Article

FZJ-2020-00033

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Combined FET PET/ADC mapping: improved imaging of glioma infiltration?

Langen, K.-J. (Corresponding author)FZJ* ; Galldiks, N.FZJ* ; Lohmann, P.FZJ*

2020
Oxford Univ. Press Oxford

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Please use a persistent id in citations: http://hdl.handle.net/2128/24497  doi:10.1093/neuonc/noz236

Abstract: Conventional MRI is the method of choice for the diagnosis of cerebral gliomas owing to its ability to detect structural changes with high spatial resolution and outstanding sensitivity. In malignant gliomas, the determination of tumor extent is primarily based on the assessment of blood–brain barrier (BBB) disruption as reflected by contrast enhancement after application of paramagnetic contrast media. In gliomas of World Health Organization (WHO) grades II and III, which are frequently non-enhancing, estimation of tumor extent relies on signal abnormalities in T2-weighted MRI or in the fluid-attenuated inversion recovery (FLAIR) sequence. It is well known, however, that neither contrast enhancement nor FLAIR abnormalities are specific for neoplastic tissue....

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)
2. Physik der Medizinischen Bildgebung (INM-4)

Research Program(s):

1. 572 - (Dys-)function and Plasticity (POF3-572) (POF3-572)

Appears in the scientific report 2020

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Database coverage:
; ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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