Journal Article

FZJ-2021-03858

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Successful treatment of thromboses of major arteries after ChAdOx1 nCov-19 vaccination

Goereci, Y. (Corresponding author) ; Kleineberg, N. N.FZJ* ; Madlener, M. ; Neuschmelting, H. ; Fink, G. R.FZJ* ; Warnke, C. ; Stetefeld, H.

2021
BioMed Central [London]

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Please use a persistent id in citations: http://hdl.handle.net/2128/28773  doi:10.1186/s42466-021-00151-y

Abstract: The ChAdOx1 nCoV-19 adenoviral vector vaccine to prevent contracting Covid-19 caused by infection with SARS-CoV-2 has been associated with vaccine-induced immune thrombotic thrombocytopenia (VITT) primarily leading to venous thromboses. Here, we report two cases of major arterial occlusions after ChAdOx1 nCov-19 vaccination, comprising a 42-year-old woman with thrombotic occlusion of the left carotid artery, and a 62-year-old man with occlusion of distal aorta and iliac arteries. Both were successfully treated with intravenous immunoglobulins and non-heparin anticoagulant agents leading to a beneficial short-term outcome of 6 weeks in case 1 and four months in case 2.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 5251 - Multilevel Brain Organization and Variability (POF4-525) (POF4-525)
2. 5252 - Brain Dysfunction and Plasticity (POF4-525) (POF4-525)

Appears in the scientific report 2021

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